Tuberculosis Research

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Graham J. Hickling
Associate Professor
Wildlife diseases affecting humans

Groups and Facilities

(1 mention)

Wildlife Health 
Emerging infectious diseases, including those that travel from animals to humans.



2016 AgResearch Faculty Awards, 10/6/2016


Recent Publications

Characterization of the Ethanol Extract of Mycobacterium avium subsp. paratuberculosis.  Bannantine, J. P., A. Wadhwa, J. Stabel, and S. Eda.  2019.  Veterinary Sciences, 6(4), 88.

Modelling bovine granuloma formation in vitro upon infection with Mycobacterium avium subspecies paratuberculosis.  Rice, J. H., M. McDaniel, A. Holland, and S. Eda.  2019.  Veterinary Sciences, 6(4), 80.

Mycobacterium avium subsp. paratuberculosis induces specific IgE production in Japanese people with allergies.  Cossu, D., S. Otsubo, S. Eda, Y. Otsubo, T. Suzuki, Y. Iwao, S. Yamamoto, T. Kuribayashi, A. Sechi, and E. Momotani.  2017.  International Journal of Inflammation, Vol. 2017, Article ID 7959154, 7 pages.

Evaluation of two in-house immunoenzymatic tests to diagnose subclinical paratuberculosis in a sheep flock in Mexicali valley, Mexico.  E. P. Barraza, T. C. Reyna, G. E. M. Basulto, C. E. A. Valadez, J. C. H. Ramirez, S. Eda, and S. Hori.  2017.  Journal of Immunoassay and Immunochemistry, 38(4):420-429.

Inferring biomarkers for Mycobacterium avium subsp. paratuberculosis infection and disease progression using experimental data.  Magombedze, G., T. Shiri, S. Eda, and J. R. Stabel.  2017.  Scientific Reports, 7:44765.

Can immune response mechanisms explain the fecal shedding patterns of cattle infected with Mycobacaterium avium subspecies paratuberculosis?.  Magombedze, G., S. Eda, S. Maarten, and A. Koets.  2016.  Plos One, 11(1):e0146844.

Quantifying Limits on Replication, Death, and Quiescence of Mycobacterium tuberculosis in Mice.  McDaniel, M., N. Krishna, W. Handagama, S. Eda, and V. Ganusov.  2016.  Frontiers in Microbiology, 7:862.

Structure determination of lipopeptides from Mycobacterium avium subspecies paratuberculosis and identification of antigenic lipopeptide probes.  Mitachi, K., L. N. S. Gautam, J. H. Rice, K. Eda, A. Wadhwa, E. Momotani, J. P. Hlopak, S. Eda, and M. Kurosu.  2016.  Analytical Biochemistry, 505:29-35.

The with-in host dynamics of Mycobacterium avium ssp. paratuberculosis infection in cattle: where time and place matter.  Koets, A., S. Eda, and S. Sreevatsan.  2015.  Veterinary Research, 46:61.

Predicting the Role of IL-10 in the Regulation of the Adaptive Immune Responses in Mycobacterium avium Subsp. paratuberculosis Infections Using Mathematical Models.  Magombedze, G., S. Eda, and J. Stabel.  2015.  PLOS One, 10 (11):e0141539.

Seroprevalence of IgG1 and IgG4 Class Antibodies Against Mycobacterium avium subsp. paratuberculosis in Japanese Population.  Otsubo, S., D. Cossu, S. Eda, Y. Otsubo, L. A. Sechi, T. Suzuki, Y. Iwao, S. Yamamoto, T. Kuribayashi, and E. Momotani.  2015.  Foodborne Pathogens and Disease, 12(10):851-6.

Competition for antigen between Th1 and Th2 responses determines the timing of the immune response switch during Mycobacterium avium subspecies paratuberculosis infection in ruminants.  Magombedze, G., S. Eda, and V. V. Ganusov.  2014.  PLoS Computational Biology, 10(1):e1003414. doi: 10.1371/journal.pcbi.1003414. Epub 2014 Jan 9.